Assistant Processor Chih-Kuang Chen

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Eng_陳致光_Chih-Kuang Chen

Associate Professor Chih-Kuang Chen

chihkuan AT mail.nsysu.edu.tw
07-5252-000 ext:4060
Education: Ph.D., Chemical and Biological Engineering,State University of New York at Buffalo
Office: Building of Materials, MS4017
Lab: MS5008/09
Website: Polymeric Biomaterials Lab
Discipline: Engineering Mathematics, Biomaterials

Speciality

Polymer chemistry, Nanomedicine, Fibrous materials, Functional polymers design and synthesis

2009/09 - 2014/02

Ph.D., Chemical and Biological Engineering
University at Buffalo, The State University of New York, US

2002/09 - 2004/06

MS., Department of Chemical Engineering
National Taiwan University, Taiwan

2000/09 - 2002/06

BS., Department of Chemical Engineering & Biotechnology
National Taipei University of Technology, Taiwan

2022/01 - present

Associate Professor
Department of Materials and Optoelectronic Science, National Sun Yat-sen University

2019/08 - 2021/12

Assistant Professor
Department of Materials and Optoelectronic Science, National Sun Yat-sen University

2018/08 - 2019/07

Associate Professor
Department of Chemical and Materials Engineering, National Yunlin University of Science and Technology

2017/02 - 2018/07

Associate Professor
Department of Fiber and Composite Materials, Feng Chia University

2014/02 - 2017/02

Assistant Professor
Department of Fiber and Composite Materials, Feng Chia University

2005/01 - 2009/07

Associate Researcher
Material and Chemical Research Laboratories, Industrial Technology Research Institute

年度	計畫名稱	擔任工作	機構	補助類別
109	具有尺寸可調控性及MMP-2/NIR/pH階段式啟動釋放特性之金奈米棒/聚乳酸複合載體之製備及其應用於抗癌藥物傳遞之研究	計畫主持人	科技部	一般研究計畫
107	具有主動標靶功能及pH/redox potential雙重響應特性之聚乳酸奈米交聯型微胞之製備及其應用於抗癌藥物傳遞之研究	計畫主持人	科技部	新進人員研究計畫
106	具有pH及氧化還原電位雙重響應特性之智慧型聚乳酸奈米微胞之製備及其應用於抗癌藥物傳遞之研究	計畫主持人	科技部	新進人員研究計畫
105	磁控包覆神經生長因子之微載體對大斷裂神經再生作用之評估	共同主持人	科技部	一般型研究計畫
104	以新穎奈米中空高分子微粒為基因/藥物共傳遞載體及其克服癌症細胞抗藥性之應用	計畫主持人	科技部	新進人員研究計畫

C. K. Chen*, M. G. Liao, Y. L. Wu, Z. Y. Fang, J. A. Chen, Preparation of highly swelling/antibacterial cross-linked N-maleoyl-functional chitosan/polyethylene oxide nanofiber meshes for controlled antibiotic release, Mol. Pharmaceutics, (2020) Accepted.
C. L. Huang, K. M. Lee, Z. X. Liu, R. Y. Lai, C. K. Chen, W. C. Chen, J. F. Hsu, Antimicrobial Activity of Electrospun Polyvinyl Alcohol Nanofibers Filled with Poly[2-(tert-butylaminoethyl) Methacrylate]-Grafted Graphene Oxide Nanosheets, Polymers, 12(7) (2020) 1449.
C. K. Chen*, P. K. Huang, W. C. Law, C. H. Chu, N. T. Chen, L. W. Lo, Biodegradable Polymers for Gene-Delivery Applications, Int. J. Nanomed., 15 (2020) 2131-2150.
C. Yang, M. Yin, G. Xu, W. J. Lin, J. Chen, Y. Zhang, T. Feng, P. Huang, C. K. Chen*, K. T. Yong, Biodegradable polymers as a noncoding miRNA nanocarrier for multiple targeting therapy of human hepatocellular carcinoma, Adv. Healthcare Mater., 8 (2019) 1801318.
C. K. Chen*, M. C. Lee, Z. I. Lin, C. A. Lee,Y. C. Tung, C. W. Lou, W. C. Law, N. T. Chen, K. Y. Lin, J. H. Lin, Intensifying the antimicrobial activity of poly[2-(tert-butylamino)ethyl methacrylate]/polylactide composites by tailoring their chemical and physical structures, Mol. Pharmaceutics, 16 (2019) 709-723.
C. Yang, K. K. Chan, G. Xu, M. Yin, G. Lin, X. Wang, W. J. Lin, M. D. Birowosuto, S. Zeng, T. Ogi, K. Okuyama, F. A. Permatasari, F. Iskandar, Y. Lin, C. K. Chen*, K. T. Yong, Biodegradable polymer coated multifunctional graphene quantum dots for light-triggered synergetic therapy of pancreatic cancer, ACS Appl. Mater. Interfaces, 11 (2019) 2768-2781.
Z. I. Lin, C. W. Lou, Y. J. Pan, C. T. Hsieh, C. L. Huang, C. K. Chen, J. H. Lin, PP/MWCNTs composites: effects of length of MWCNTs on isothermal crystallization behaviors, crystalline structure, and thermal stability, J. Compos. Mater., 52 (2018) 503–517.
C. H. Chang, C. Y. Tsai, W. J. Lin, Y. C. Su, H. J. Chuang, W. L. Liu, C. T. Chen, C.K. Chen*, B. T. Ko, Alternating copolymerization of epoxides with carbon dioxide or cyclic anhydrides using bimetallic nickel and cobalt catalysts: preparation of hydrophilic nanofibers from functionalized polyesters, Polymer, 141 (2018) 1-11.
J. H. Lin, M. C. Lee, C. K. Chen, C. L. Huang, Y. S. Chen, S. P. Wen, S. T. Kuo, C. W. Lou, Recovery evaluation of rats' damaged tibias: implantation of core-shell structured bone scaffolds made using hollow braids and a freeze-thawing process, Mater. Sci. Eng., C, 79 (2017) 481-490.
C. Yang, K. K. Chan, W. J. Lin, A. M. Soehartono, G. Lin, H. Toh, H. S. Yoon, C. K. Chen*, K. T. Yong, Biodegradable nanocarriers for small interfering ribonucleic acid (siRNA) co-delivery strategy increase the chemosensitivity of pancreatic cancer cells to gemcitabine, Nano Res., 10 (2017) 3049-3067.
G. Lin, C. K. Chen*, F. Yin, C. Yang, J. Tian, T. Chen, G. Xu, C. He, J. Wang, F. Lu, X. Wang, K. T. Yong, Biodegradable nanoparticles as siRNA carriers for in vivo gene silencing and pancreatic cancer therapy, J. Mater. Chem. B, 5 (2017) 3327-3337.
C. K. Chen*, W. J. Lin, Y. Hsia, L. W. Lo, Synthesis of polylactide-based core–shell interface cross-linked micelles for anticancer drug delivery, Macromol. Biosci., 17 (2017) DOI: 10.1002/mabi.201600191.
C. K. Chen*, S. C. Huang, Preparation of reductant–responsive n-maleoyl-functional chitosan/poly(vinyl alcohol) nanofibers for drug delivery, Mol. Pharmaceutics, 13 (2016) 4152-4167.
K. Y. A. Lin, B. J. Chen, C. K. Chen*, Evaluating prussian blue analogues MII3[MIII(CN)6]2 (MII = Co, Cu, Fe, Mn, Ni; MIII = Co, Fe) as activators for peroxymonosulfate in water, RSC Adv., 6 (2016) 92923-92933.
R. Aalinkeel, B. Nair, C. K. Chen, S. D. Mahajan, J. L. Reynolds, H. Zhang, H. Sun, D. E. Sykes, K. C. Chadha, S. G. Turowski, K. D. Bothwell, M. Seshadri, C. Cheng, S. A. Schwartz, Nanotherapy silencing the interleukin-8 gene produces regression of prostate cancer by inhibition of angiogenesis, Immunology, 148 (2016) 387-406.
C. Yang, N. Panwar, Y. Wang, B. Zhang, M. Liu, H. Toh, H. S. Yoon, S. C. Tjin, P. H. J. Chong, W. C. Law, C. K. Chen*, K. T. Yong, Biodegradable charged polyester-based vectors (BCPVs) as an efficient non-viral transfection nanoagent for gene knockdown of the BCR–ABL hybrid oncogene in a human chronic myeloid leukemia cell line, Nanoscale, 8 (2016) 9405-9416.
H. Sun, C. K. Chen, H. Cui, C. Cheng, Crosslinked polymer nanocapsules, Polymer International, 65 (2016) 351-361.
J. H. Lin, Z. I. Lin, Y. J. Pan, C. L. Huang, C. K. Chen, C. W. Lou, Polymer composites made of multi-walled carbon nanotubes and graphene nano-sheets: effects of sandwich structures on their electromagnetic interference shielding effectiveness, Composites, Part B, 89 (2016) 421-431.
A. B. Hill, M. Chen, C. K. Chen, B. A. Pfeifer, C. H. Jones, Overcoming gene-delivery hurdles: physiological considerations for nonviral vectors, Trends Biotechnol., 34 (2016) 91-105.
J. H. Lin, Z. I. Lin, Y. J. Pan, C. K. Chen, C. L. Huang, C. H. Huang, C. W. Lou, Improvement in mechanical properties and electromagnetic interference shielding effectiveness of PVA-based composites: synergistic effect between graphene nano-sheets and multi-walled carbon nanotubes, Macromol. Mater. Eng., 301 (2016) 199-211.

C. K. Chen*, Z.-I. Lin, Y.-T. Li, Preparation of polylactide-based nanoformulations for cancer therapy applications, FAPS 2019 Polymer Congress, 2019, Howard Civil International House, Taipei, Taiwan.
Z.-I. Lin, R.-P. Liu, Z.-T. You, C. K. Chen*, Antimicrobial Nanofibrous Materials for Biomedical Applications, FAPS 2019 Polymer Congress, 2019, Howard Civil International House, Taipei, Taiwan.
C. K. Chen*, Z.-I. Lin, Y.-T. Li, P.-K. Huang, C.-H. Lu, Synthesis of pH/redox dual-responsive polylactide cross-linked micelles with a targeting ability for anticancer drug delivery, SCEJ 84th Annual Meeting, 2019, Tokyo, Japan.
C. K. Chen*, W.-J. Lin, P.-K. Huang, R.-Z. Chen, H.-Y. Hsieh, R.-Y. Yang, Y.-R. Lin, Synthesis of pH/redox dual responsive polylactide nanocarriers for drug delivery applications, 2018 Global Conference on Polymer and Composite Materials (PCM 2018), 2018, Kitakyushu, Japan.
C. K. Chen*, S.-C. Huang, Y.-T. Lin, W.-J. Lin, C.-N. Hsu,W,-S, Liao, Preparation of Chitosan /Polyethylene Oxide Nanofibers for Wound Healing Materials, ATC-14 Asian Textile Conference, 2017, Kowloon, Hong Kong.
C. K. Chen* (Invited Speaker), Polylactide as a Versatile Nanocarrier for Therapeutic Agent Delivery, The 2016 International Symposium for Advanced Materials Research (ISAMR 2016), 2016, Sun Moon Lake, Taiwan.
S.-C. Huang, Y.-T. Lin, X. H. Lu, C. K. Chen*, Using an Acid-Free Process to Prepare PEO/CS Nanofibers, The 1st International Symposium on Advanced Fiber Technology and Material Application, 2016, Taichung, Taiwan.
W.-J. Lin, Y.-C. Tsai, C.-N. Hsu, J.-B. Huang, P.-K. Huang, C. K. Chen, Synthesis of crosslinked micelles for drug delivery, The 1st International Symposium on Advanced Fiber Technology and Material Application, 2016, Feng Chia University, Taichung, Taiwan.
Z.-I. Lin, Y.-C. Tung, C.-A. Lee, C. H. Lu, C. K. Chen, Preparation of antimicrobial composites, The 1st International Symposium on Advanced Fiber Technology and Material Application, 2016, Feng Chia University, Taichung, Taiwan.

校內榮譽

年度	獎項名稱	頒獎單位
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